Cathepsin L anticorps

N° du produit ABIN7670502

L’anticorps Lapin Polyclonal anti-Cathepsin L a été validé pour IHC. Il convient pour détecter Cathepsin L dans des échantillons de Humain.

Aperçu rapide pour Cathepsin L anticorps (ABIN7670502)

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin L est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-Cathepsin L anticorps

Fonction: Cathepsin L Polyclonal Antibody

Purification: Antigen Affinity Purification

Immunogène: Recombinant Human Cathepsin L protein expressed by Mammalian

Isotype: IgG

Information d'application

Indications d'application: IHC 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % proclin 300, 1 % protective protein and 50 % glycerol, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur Cathepsin L

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Autre désignation: Cathepsin L

Sujet: CATL,CATL1,CTSL,CTSL1,Cathepsin L1,Cathepsin L1 light chain,CathepsinL,FLJ31037,MEP,MGC123162,Major excreted protein,cathepsin L,cb15,ctsl1b,hgg1,The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades